Home
Focus Areas
About Us
Liver disease is a "huge global health problem" with an estimated 1.5 billion people worldwide affectedand no treatment has worked yet, Dr. Prakash Ramachandran writes in the Conversation.
That's because different factors are at play in different stages of the disease, which can lead to cirrhosis, cancer, and liver failure.
One of the biggest factors is fibrosis, which is caused by damage to the liver's epithelial cells.
It can take years for the disease to develop, and no treatment has worked yet.
But Ramachandran and his team at the University of Edinburgh are reporting in the Proceedings of the National Academy of Sciences that they've found a way to map out fibrosis in a way that could lead to new treatments.
They're calling it Liver Cell Analysis, or LiCA, which allows them to take a patient's liver biopsy and blood samples and "build up a high-resolution profile of changes in cells, genes, and proteins in different types of liver disease and at different stages of disease progression," as Ramachandran puts it.
"This means we can nail down which pathways in the liver are associated with different clinical outcomes in a way others cannot."
The team has already started a clinical trial of LiCA in patients with non-alcoholic fatty liver
Selected Grant News Headlines
A customized collection of grant news from foundations and the federal government from around the Web.
"It takes a village to raise a child,"Jenna Bland writes in the Chicago Sun-Times. "The answer lies in the widespread access to free digital platforms that enable individuals to convene around...more
The concept of a "smart hospital" has been around for a while, but a survey released this month by the College of Healthcare Information Management Executives and digital health company Care.ai...more
More than half of America's billion-dollar startup companies trace their roots to immigrant entrepreneurs, and a new study finds that immigrants based in the US are more likely to relocate to Canada...more
New Jersey's largest and most comprehensive health network has the most researchers in the state, according to NJBIZ's list of the top research centers in the state. Hackensack Meridian Health,...more
In 2018, Virginia's Inova Health System announced plans to transform the former ExxonMobil headquarters in Merrifield into a "vibrant innovation district with dynamic academic and research spaces,...more
The largest rural health system in the US plans to open a $350 million virtual care center in Sioux Falls, South Dakota, this fall. The Sanford Virtual Care Center will feature a patient and...more
Royal Philips Electronics is taking a page out of Al Gore's book with a pledge to cut its greenhouse-gas emissions by a third by 2024. In a blog post, the Dutch company says it plans to reduce...more
"We are excited to welcome these startups to TMC as companies are making significant strides in drug discovery and health tech developments," Devin Dunn, head of the Accelerator for Health Tech at...more
Dr.Vin Gupta, Amazon's chief medical officer, recently gave the keynote speech at Sanford Health's annual meeting in Sioux Falls, South Dakota, and he had some interesting things to say about the...more
If you're struggling with depression, anxiety, or other mental-health issues, now is the time to see a therapist. Relief Mental Health, which has 10 clinics in three states, is offering...more
Social Entrepreneurship
Spotlight
Influencing Social Good Through Retail
When Hannah Davis traveled to China to teach English, she noticed how Chinese workers and farmers were often sporting olive green army-style shoes. Those shoes served as her inspiration to create her own social enterprise, Bangs Shoes.
