Home
Focus Areas
About Us
Liver disease is a "huge global health problem" with an estimated 1.5 billion people worldwide affectedand no treatment has worked yet, Dr. Prakash Ramachandran writes in the Conversation.
That's because different factors are at play in different stages of the disease, which can lead to cirrhosis, cancer, and liver failure.
One of the biggest factors is fibrosis, which is caused by damage to the liver's epithelial cells.
It can take years for the disease to develop, and no treatment has worked yet.
But Ramachandran and his team at the University of Edinburgh are reporting in the Proceedings of the National Academy of Sciences that they've found a way to map out fibrosis in a way that could lead to new treatments.
They're calling it Liver Cell Analysis, or LiCA, which allows them to take a patient's liver biopsy and blood samples and "build up a high-resolution profile of changes in cells, genes, and proteins in different types of liver disease and at different stages of disease progression," as Ramachandran puts it.
"This means we can nail down which pathways in the liver are associated with different clinical outcomes in a way others cannot."
The team has already started a clinical trial of LiCA in patients with non-alcoholic fatty liver
Selected Grant News Headlines
A customized collection of grant news from foundations and the federal government from around the Web.
One of Australia's most high-profile business leaders is leaving his post at the Australian Securities Exchange to lead the country's largest anti-slavery organization. David Braga, who has...more
"The New Venture Competition provides a rigorous platform through which students develop their business ideas as a positive force for change," says Elise Bates, the new director of Harvard Business...more
Foundation: Whitefish Community Foundation
"Through our collective efforts, we're not just providing financial support, but we're investing in Montana's vitality and resilience." That from Mike Smith, president of Glacier Bank, which...more
Foundation: Community Foundation of Broward
Ten nonprofit organizations in South Florida are getting a total of $300,000 in grants thanks to a new fund meant to fight discrimination in the LGBTQ community. The Our Fund Foundation and the...more
"It's more than just food and water and shelter, we now know that as a society, we now know that as a society." That's what an Alaska school board member has to say about a bill that would...more
When Gladys Markus graduated from her accounting course at Nigeria's Plateau State University last year, she had one thing on her mind: Starting a food business. The then-22-year-old had been...more
Badari Ambatti and his wife, Roopa Hhaprakash, moved from Bengaluru, India, to Garden City Park in New York about 10 years ago, and since then, they've made a home for themselves and their daughter,...more
"People used to go swimming in it, and then how grateful [they] are for the work that we're doing in conjunction with the government and other organizations," Mike Smith tells This Week in...more
"A nutritious breakfast isn't just about filing empty stomachs; it's about nourishing young minds." That's what Vicki Cutler, a branch manager at Prospera Credit Union in British Columbia, had to...more
Devin Booker is making good on his promise to give $2.5 million to Arizona nonprofits over the next five years. The NBA player and the Phoenix Suns have announced the recipients of the 2023-24...more
Health News from...
Gates Foundation
Whitefish Community Foundation
Community Foundation of Broward
Central Valley Community Foundation
Rhode Island Foundation
Porter County Community Foundation
Changemakers
Luzerne Foundation
Community Foundation of Western North Carolina
Winona Community Foundation
Social Entrepreneurship
Spotlight
Why People Buy from Social Enterprises?
The Guardian has compiled a list of responses to its latest open thread, and has announced the winner of the social enterprise gift hamper packed with presents.
